Pharmaceutical Intermediates

calciferol

API name

Product name

CAS NO

Alfacalcidol

(1R,3aR,7aR)-7a-Methyl-1-((R)-6-Methylheptan-2-yl)hexahydro-1H-inden-4(2H)-one

66251-18-1

details

(3aR)-1t-((R)-1,5-Dimethyl-hexyl)-7a-methyl-(3ar,7at)-hexahydro-indan-4t-ol

33813-99-9

details

tert-butyldimethyl(((1S,E)-3-((E)-2-((1S,3aS,7aR)-7a-methyl-1-(6-methylheptan-2-yl)hexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexyl)oxy)silane

87649-55-6

details

tert-butyldimethyl(((1S,E)-3-((E)-2-((1S,3aS,7aR)-7a-methyl-1-(6-methylheptan-2-yl)hexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexyl)oxy)silane

87649-55-6

details

[[(1a,3b,5e,7e)-9,10-secocholesta-5,7,10(19)-triene-1,3-diyl]bis(oxy)]bis[(1,1-dimethylethyl)dimethylsilane]

108887-35-0

details

Alfacalcidol

41294-56-8

details

Doxercalciferol

25-Hydroxyvitamin D2

21343-40-8

details

1α,25-Dihydroxy vitamin D2

60133-18-8

details

Calcipotriol

Calcipotriol monohydrate

147657-22-5

details

Calcipotriol

112965-21-6

details

24-Cycloproyply-1,3-bis[[(1,1-dimethylethyl)dimethylsily]oxy]-9,10-secochola-5,7,10(19),22-tetraen-24-ol

112849-27-1

details

(R,E)-4-((1R,3aS,7aR,E)-4-((E)-2-((3S,5R)-3,5-bis((tert-butyldimethyl-silyl)oxy)-2-methylenecyclohexyl-idene) ethylidene)-7a-methyl octahydro-1H-inden-1-yl)-1-cyclopropylpent-2-en-1-one

112849-17-9

details

1,3-bis-TBDMS-5,6-trans-noralcohol

128387-35-9

details

Inecalcitol

163217-09-2

details

Enecalcidol CD ring

N/A

details

(1R,3R)-1,3-bis((tert-butyldimethyl)silanyloxy)-5-[2-(diphenylphosphinoyl)-ethylidene]cyclohexane

139356-39-1

details

Tacalcitol

57333-96-7

details

Tacalcitol monohydrate

93129-94-3

details

Maxacalcitol

103909-75-7

details

(1S,3aR,4S,7aS)-1-((S)-1-(3-hydroxy-3-methylbutoxy)ethyl)-7a-methyloctahydro-1H-inden-4-ol

192573-37-8

details

Phosphine oxide,[(2Z)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethyl]diphenyl-; Phosphineoxide, [2-[3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethyl]diphenyl-,[3S-(1Z,3a,5b)]-

81522-68-1

details

[3S-(1Z,3α,5β)]-2-[3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethanol

81506-24-3

details

Calcifediol

Calcifediol hydrate

63283-36-3

details

Calcitriol

TEI-9647/(5S)-5-[(2R)-2-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]propyl]-3-methylideneoxolan-2-one

173388-20-0

details

5-((R)-2-((1R,3aS,7aR,E)-4-((Z)-2-((3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)propyl)-3-methylenedihydrofuran-2(3H)-one

593245-62-6

details

Pefcalcitol

381212-03-9

details

1-Cyclopropyl-2-(triphenylphosphoranylidene)ethanone

7691-76-1

details

Atocalcitol

302904-82-1

details

(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-(4-ethyl-4-hydroxyhexoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

131875-08-6

details

25-Hydroxyvitamin D3

19356-17-3

details

TBS / 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol

140710-96-9

details

Calcitriol

32222-06-3

details

5,6-trans-Calcitriol

73837-24-8

details

Ethyl (5R)-((1R,3aS,7aR,E)-4-((E)-2-((3S,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)hexanoate

169900-32-7

details

Seocalcitol

134404-52-7

details

Seocalcitol CD ring

189102-33-8

details

Falecalcitriol

83805-11-2

details

Eldecalcitol

(5Z,7E)-(1R,2R,3R)-1,3-bis(tert-butyldimethylsilyloxy)-2-(3-tert-butyldimethylsilyloxypropoxy)-25-triethylsilyloxy-9,10-secocholesta-5,7,10(19)-triene

933779-95-4

details

Eldecalcitol

104121-92-8

details

(1R,3aR,7aR)-1-[(1R)-1,5-Dimethyl-5-[(triethylsilyl)oxy]hexyl]octahydro-7a-methyl-4H-inden-4-one

144848-24-8

details

(1R,3aR,4S,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-4-ol

66774-84-3

details

(Z)-[2-{(3R,4R,5R)-3,5-bis(tert-butyldimethylsilanyloxy)-2-methylene-4-(3-(tert-butyldiphenylsilanyloxy)propoxy)cyclohexylidene}ethyl]diphenylphosphine oxide

1254276-84-0

details

((Z)-2-((3R,4R,5R)-3,5-bis((tert-butyldimethylsilyl)oxy)-4-(3-((tert-butyldimethylsilyl)oxy)propoxy)-2-methylenecyclohexylidene)ethyl)diphenylphosphine oxide

200636-54-0

details

Cholesta-5,7-dien-3-ol, 1,2-epoxy-, (1α,2α,3β)-;1alpha,2alpha-epoxy-3beta-hydroxy-5,7-cholestadiene

104109-72-0

details

Other intermediates of ossification alcohols

(S,Z)-(2-(5-((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethyl)diphenylphosphine oxide

100858-27-3

details

TBS / (S)-2-((1R,3aR,4S,7aR)-4-((tert-butyldimethylsilyl)oxy)-7a-methyloctahydro-1H-inden-1-yl)propan-1-ol

100928-03-8

details

(1R,3aR,4S,7aR)-1-((S)-1-Hydroxypropan-2-yl)-7a-methyloctahydro-1H-inden-4-ol

64190-52-9

details

prostaglandin

API name

Product name

CAS NO

Latanoprost/ Bimatoprost

(3aR,4R,5R,6aS)-5-((tert-butyldimethylsilyl)oxy)-4-((S,E)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one

1240483-15-1

details

[1,1'-Biphenyl]-4-carboxylic acid, (3aR,4R,5R,6aS)-hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl] -2-oxo-2H-cyclopenta[b]furan-5-yl ester

41639-73-0

details

[1,1'-Biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-5-phenyl-1-pentenyl]-2H-cyclopenta[b]furan-5-yl ester

41639-72-9

details

Latanoprost

130209-82-4

details

(3aR,4R,5R,6aS)-5-(tert-butyldimethylsilyloxy)-4-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one

1240483-21-9

details

Travoprost

157283-68-6

details

(3aR,4R,5R,6aS)-5-(tert-butyldimethylsilyloxy)-4-((R,E)-3-(tert-butyldimethylsilyloxy)-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-one

1240483-24-2

details

Tafluprost

209860-87-7

details

[1,1′-Biphenyl]-4-carboxylic acid, (3aR,4R,5R,6aS)-4-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl ester

2226086-11-7

details

(3aR,4R,5R,6aS)-2-Oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate

79171-99-6

details

Limaprostst

[(4S)-4-Methyl-2-oxooctyl]phosphonic acid dimethyl ester

102276-54-0

details

Limaprostst

74397-12-9

details

Triphenyl(3-phenylmethoxypropyl)phosphanium,bromide

54314-85-1

details

2-Heptenoic acid, 7-[(1R,2R,3R,5S)-5-(acetyloxy)-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-3-[(tetrahydro-2H-pyran-2-yl)oxy]cyclopentyl]-, methyl ester, (2E)-

1574525-36-2

details

Lubiproston

Lubiprostone

136790-76-6

details

Bimatoprost

155206-00-1

details

Carboprost tromethamine

Carboprost methylate

62776-96-9

details

Carboprost tromethamine

58551-69-2

details

Prostaglandin E2

Prostaglandin F2α

551-11-1

details

prostaglandin E2

363-24-6

details

(3aR,4R,5R,6aS)-5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-4-[(1E,3S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-octen-1-yl]hexahydro-2H-cyclopenta[b]furan-2-one

61628-05-5

details

[1,1'-Biphenyl]-4-carboxylic acid, (3aR,4R,5R,6aS)-hexahydro-4-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2-oxo-2H-cyclopenta[b]furan-5-yl ester

51014-26-7

details

Sulprostone

60325-46-4

details

JAK Inhibitor

API name

Product name

CAS NO

tofacitinib

4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

479633-63-1

details

Tofacitinib citrate

540737-29-9

details

2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine

90213-66-4

details

4-Chloropyrrolo[2,3-d]pyrimidine

3680-69-1

details

(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine ((2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinate) (2:1)

477600-71-8

details

(3R,4R)-1-Benzyl-N,4-diMethylpiperidin-3-Amine dihydrochloride

1062580-52-2

details

baricitinib

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

269410-08-4

details

2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile

1187595-85-2

details

Baricitinib phosphate

1187595-84-1

details

rituxetinib

tert-butyl (2S,5R)-5-amino-2-methylpiperidine-1-carboxylate

1792190-72-7

details

Serpatinib

3,6-Diazabicyclo[3.1.1]heptane-6-carboxylic acid tert-butyl ester

869494-16-6

details

filgrastinib

Filgotinib

1206161-97-8

details

Thiomorpholine-1,1-dioxide

39093-93-1

details

4-(Bromomethyl)benzeneboronic acid pinacol ester

138500-85-3

details

Cyclopropanecarboxylic acid (5-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-amide

1142943-96-1

details

Upatinib

(3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester

1428243-26-8

details

N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic acid ethyl ester

1869118-24-0

details

N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic acid 1,1-dimethylethyl ester

1201187-44-1

details

Irrutinib

Ibrutinib

936563-96-1

details

(S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine

143900-44-1

details

5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine

330786-24-8

details

3-Bromo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

83255-86-1

details

1H-Pyrazole-4-carbonitrile, 3-amino-

16617-46-2

details

1-Boc-3-hydroxypiperidine

85275-45-2

details

ruxolitinib

Ruxolitinib

941678-49-5

details

3-Cyclopentylacrylonitrile

591769-05-0

details

Cardio-Cerebrovascular

API name

Product name

CAS NO

perindopril

Perindopril erbumine

107133-36-8

details

N-[(S)-1-Carbethoxy-1-butyl]-(S)-alanine

82834-12-6

details

(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic Acid

80875-98-5

details

(S)-indoline-2-carboxylate

79815-20-6

details

Indoline-2-carboxylic acid

78348-24-0

details

Fimasartan

247257-48-3

details

2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-5-pyrimidineacetamide

503155-67-7

details

2-(2-butyl-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide

1315478-13-7

details

ticagrelor

(1R,2R)-2-(3,4-difluorophenyl)cyclopropanamine(S)-(carboxylato(phenyl) methyl)holmium

376608-71-8

details

4-Biphenyl

4-Bromobiphenyl

92-66-0

details

Shakuba/LCZ696

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid

1012341-48-8

details

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid

1012341-50-2

details

(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate

1426129-50-1

details

bumetanide

4-Chloro-3-nitro-5-sulphamoylbenzoic acid

22892-96-2

details

benazepril

L-Homophenylalanine

943-73-7

details

Ethyl (S)-2-amino-4-phenylbutanoate hydrochloride

90891-21-7

details

Antibacterial and Antiviral

API name

Product name

CAS NO

posaconazole

4-Chloro-benzenesulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl ester

175712-02-4

details

PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE

184177-81-9

details

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one

171228-49-2

details

1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one

184177-83-1

details

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

149809-43-8

details

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one

1887197-42-3

details

[S-(R',R')]-2,3-Bis(benzoyloxy)butanedioic acid compd. with[S-(R',R')]-[1-ethyl-2-(phenylmethoxy)propyl]hydrazine

183871-36-5

details

esaconazole

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide

368421-58-3

details

N-Methyl-N-(3-[((N-tert-butoxycarbonyl-N-methylamino)acetoxy)methyl]pyridin-2-yl)carbamic acid 1-chloroethyl ester

338990-31-1

details

(2-(Methylamino)pyridin-3-yl)methyl2-((tert-butoxycarbonyl)(methyl)amino)acetate

1180002-01-0

details

2-(Methylamino)pyridine-3-methanol

32399-12-5

details

2-Bromo-4-cyanoacetophenone

20099-89-2

details

amorolfine

Cis-2,6-Dimethylmorpholine

6485-55-8

details

doravirine

2-CHLORO-3-FLUORO-4-(TRIFLUOROMETHYL)PYRIDINE

628692-22-8

details

oseltamivir

Oseltamivir phosphate

204255-11-8

details

(3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate hydrochloride

651324-08-2

details

Ethyl (1S,5R,6S)-5-(pentan-3-yl-oxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylate

204254-96-6

details

Finafloxacin

Ethyl 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate

117528-64-0

details

ofloxacin

2,4-Dichloro-3-methylbenzoic acid

83277-23-0

details

Cefthoram picol

4-Methylthiazole-5-carboxylic acid ethyl ester

20582-55-2

details

Psychotic Depression

API name

Product name

CAS NO

vilazodone

3-(4-Chlorbutyl)-1H-indol-5-carbonitril

143612-79-7

details

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate

163521-20-8

details

Duloxetine

1-fluoronaphthalene

321-38-0

details

(S)-3-(methylamino)-1-(thiophen-2-yl)propan-1-ol

116539-55-0

details

asenapine

2-(5-Chloro-2-phenoxyphenyl)acetic acid

70958-20-2

details

Trans-(+/-)-11-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

129385-59-7

details

11-chloro-2,3-dihydro-2-methyl-1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

1012884-46-6

details

Perampanel

2-Cyanobenzeneacetic acid

18698-99-2

details

oxazepam

2-(2-amino-5-bromobenzoyl) pyridine

1563-56-0

details

Metabolism Related

API name

Product name

CAS NO

Saborisat sodium

8-Bromooctanoic acid

17696-11-6

details

Ethyl 8-bromooctanoate

29823-21-0

details

8-Chloro-octanoic acid ethyl ester

105484-55-7

details

Carsalam

2037-95-8

details

SNAC / Sodium,8-[(2-hydroxybenzoyl)amino]octanoate

203787-91-1

details

Imeglumine hydrochloride

IMegliMin

775351-65-0

details

Alagliptin

2-Methylpyrazolo[1,5-a]pyriMidine-6-carboxylic acid

739364-95-5

details

Other

API name

Product name

CAS NO

Vonorazan

5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile

1240948-77-9

details

5-(2-fluorophenyl)-1H-Pyrrole-3-carboxaldehy

881674-56-2

details

Pyridine-3-sulfonyl chloride

16133-25-8

details

Vonoprazan

1260141-27-2

details

ketoprofen

Methyl 3-methylbenzoate

68432-92-8

details

m-(1-Cyanoethyl)benzoic acid

5537-71-3

details

Sotolacib

3-Pyridinamine,4-methyl-2-(1-methylethyl)-

1698293-93-4

details

7-chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

2252403-82-8

details

Cefaloridine

2-Thiopheneacetic acid

1918-77-0

details

2-Thiopheneacetyl chloride

39098-97-0

details

pantethine

Pantethine

16816-67-4

details

SPDP/ADC linker

SPDP

68181-17-9

details

lurasidone

(1R,2R)-1,2-Cyclohexanedicarboxylic acid

46022-05-3

details

(1R,2R)-1,2-Cyclohexanedimethanol

65376-05-8

details

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Products

Pharmaceutical Intermediates

calciferol

prostaglandin

JAK Inhibitor

Cardio-Cerebrovascular

Antibacterial and Antiviral

Psychotic Depression

Metabolism Related

Other

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